Controlling the Interfacial Biology Between the Gingiva and the Tooth/Implant Holds Novel Perspectives to Deal With Periodontal Disease (Wed 16:00)
The junctional epithelium seals off the tooth supporting tissues from the aggressive oral environment; its disruption is a primary event in the onset of periodontal disease (PD). This lecture will present our research aimed at elucidating how epithelial cells of the gingiva build a sealing interface. We believe that a better understanding of the interfacial biology between the gingiva and the tooth/implant holds the key to a change in paradigm for Periodontal Disease treatment from the current management approach to one based on prevention and early intervention, and promises to pave the way for innovative preventive and therapeutic treatments.
Professor Antonio Nanci is a graduate of Université de Montreal (MSc Pathology) and McGill University (PhD Anatomy and Cell Biology) with postgraduate training at University of Southern California in Craniofacial Developmental Biology. He is a Professor at the Faculty of Dental Medicine of Université de Montréal since 1983, Director of the Laboratory for the Study of Calcified Tissues and Biomaterials and of the Electron Imaging Unit of the University. He was Vice-dean Research and is currently Director of the Department of Stomatology. His research interests are the basic cell biological processes of normal and pathological calcified tissues, tissue regeneration, and the integration of biomaterials.
He is the author of Ten Cate’s Oral Histology: Development, Structure, and Function.
For many dentistry students, basic formation subjects represent dull but unavoidable steps prior to obtaining access to their subjects of interest. Even many clinical teachers cannot see the value of good basic scientific formation. To many, it seems that the clinician realm is only restricted to good diagnosis, planning and treatment. However, decision-making during these processes should be based on scientific evidence. Without comprehensive basic formation, the critical thinking needed to separate the wheat from the chaff cannot be granted, and may negatively impact clinical practice.
Eddie Rodríguez-Carballo completed the degree of Dentistry in 2006 and a Master's in Biomedicine in 2008. He worked as a clinical practitioner for three years. However, he always had strong interests in basic research. Eddie obtained a PhD in biomedicine at the laboratory of Prof Francesc Ventura (University of Barcelona) in 2013. The topic of his research was the roles of BMP, Wnt and p38 during mesenchymal stem cell differentiation and osteoblast commitment. Currently he is working as a postdoctoral researcher at the laboratory of Prof Denis Duboule (University of Geneva), studying 3D genome organization during limb development.
Jacques-Olivier Pers (DD, PhD)
The Dentist and systemic autoimmune Pathologies: How to best co-operate (Fri 16:00)
Still unfamiliar to the general public, autoimmune diseases affect nearly 5% of the population and are the cause of various clinical manifestations not sparing the orofacial area. For example, in Sjogren's syndrome, which is characterized by impairment of the exocrine glands, particularly the salivary glands, oral manifestations are prominent with the existence of xerostomia which heavily impacts the patients quality of life. Furthermore, several studies suggest that the presence of Porphyromonas gingivalis, a major periodontopathogenic bacteria may be involved in the development of rheumatoid arthritis and B-cell-targetted immunotherapies in rheumatoid arthritis improves periodontitis.
The link between diabetes and oral health is also very important because periodontal treatment may have the effect of a drug on diabetes.
These few elements clearly highlight the key role of the dentist in the multidisciplinary management of these patients but also in the diagnosis, the stabilization or even the prevention of some of these diseases.
Professor Jacques-Olivier Pers is the director of the INSERM research team ERI29 “Immunotherapy and B cell pathologies”, since October 2011. This Laboratory belongs to the LABEX “Immunotherapy, graft, oncology”. He is also the chair of the Scientific Council for the French Institute for Dental Research (IFRO).
Since 1997 he has been involved in the field of B cells in autoimmune diseases. His studies have yielded 133 original articles and reviews which have contributed to improve the understanding of the characterization of B cell functions in autoimmunity and most particularly in Sjögren's syndrome and the contribution of BAFF to autoimmunity.
His research group perpetuate the platform of immunopathology and immunotherapy dedicated to the study of normal and pathological B cells. Different models are studied: autoimmune diseases (Sjögren’s syndrome, systemic lupus erythematosus, rheumatoid arthritis), lymphoproliferative disorders (chronic lymphocytic leukemia), kidney graft rejection and periodontal diseases from upstream approaches (epigenetics and autoimmunity, the genetic control of BAFF, calcium signaling, regulatory B cells) to downstream approaches (multicenter clinical trials, IVIg, valorization).
Eugene L. Anderson, Ph.D.
A Closer Examination of Dental Education in Europe (Fri 09:00)
Currently there exist little comprehensive data regarding dental education in Europe. There is no clear understanding regarding student and faculty demographics, the length of programs, the use of technology and curricular integration. In June 2016, ADEE launched the first comprehensive survey of dental education among ADEE members in Europe. The survey findings will be of use not only to ADEE in its work in the European Commission Arena, but also be of considerable value to member schools for meaningful self-bench marking processes.
The aim of this presentation is to present preliminary findings of the survey and discuss next steps in interpreting the findings.
Eugene L. Anderson, Ph.D., is a higher education policy expert and consultant. He previously served as the Chief Policy Officer and Managing Vice President at the American Dental Education Association. In this role he led the ADEA Policy Center (APC) and integrated the Association’s educational research, access and diversity programming and public policy advocacy activities to address contemporary issues facing dental education and the oral health needs of the public. He also helped to lead national policy changes through the ADEA Commission on Change and Innovation in Dental Education (ADEA CCI).
Dr. Paula Vassallo
Platform for Better Oral Health in Europe (Fri 09:00)
The Platform for Better Oral Health, established in 2011, is a joint initiative representing professional, student, and scientific organisations across Europe under the auspices of a shared mission to improve oral health and enhance cost-effective prevention of oral disease. In working toward a common European approach for oral health education, promotion, and access to care, the Platform strives to enhance the EU’s oral health policy, encourage oral health and prevention of oral disease, secure EU action on oral health, and address oral health inequalities and challenges. We believe that our approach toward better oral health must be supported by improved data collection in all Member States and the exchange of best practices at the EU level.
The Platform has created an online repository of best practices in oral health from across the EU, a project that is still ongoing and aims to provide an opportunity for exploring what countries are doing nationally. This carries the potential of driving change across other Member States and improving the oral health of citizens across Europe. We are striving to ensure that policymakers and national governments have a good overview of the status of oral health in Europe and how its incorporation into broader health policy can be of benefit for citizens and lead to cost-efficiencies in Europe. To measure the improvements made, the Platform has created a set of 2020 targets to assess how the EU has improved in terms of creating better data collection systems, prevention policies, and education and awareness-raising. As we work with stakeholders to make strides towards these goals, the Platform maintains engagement in discussions on oral health in Europe and provides resources of evidence-based information and policy guidance on oral health.
Dr. Paula Vassallo received her degree in Dentistry from the University of Malta in 1992 and has been practicing as a dentist since 1993. She also holds a Diploma in Dental Public Health from the Royal College of Surgeons of England, a Master of Science in Dental Public Health from the University College London and an MBA from the Warwick Business School. In 2011 she was elected Fellow of the Faculty of Public Health of the Royal Colleges of Physicians of the United Kingdom.
Dr. Vassallo holds an appointment as Consultant in Dental Public Health with the Government of Malta and is actively involved in promoting oral health in Malta. She is a lecturer and course co-ordinator in Preventive and Community Dentistry and Dental Public Health at the University of Malta.
Dr Vassallo represents Malta at the European meetings for Chief Dental Officers. She is a member of the health research group of the Institute of Small Island States which is based in Malta. She is Past President of the Council of European Chief Dental Officers and is currently Chairperson of the Platform for Better Oral health in Europe. She has also chaired the Working Group of Oral Health in The CED (Council of European Dentists) and was responsible for guiding the development of CED policies related to oral health issues.
She has recently been appointed as Director of Health Promotion and Disease Prevention in Malta.